BACKGROUND: Current outcomes from catheter ablation for scar-dependent ventricular tachycardia (VT) are limited by high ...

With the advancements of molecular genetics and the identification of mutations in the genes encoding the cardiac ryanodine receptor and cardiac calsequestrin 2 in patients with CPVT, the central role ...

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...

We aim to provide the reader with an overview of the genes and corresponding biological pathways that have been found to be implicated in rare and common forms of SVD. We have elected to categorize ...

Noninducibility of any VT at PES* Established predictive value when performed from multiple sites (RV and LV) ≤3 extrastimuli Not useful for patients without inducible VT; suboptimal negative ...

The optimal grading scale must demonstrate (1) a strong correlation with clinical outcome, (2) simplicity and feasibility of scale interpretation while ensuring characterization of relevant ...

Our vision is to innovate and incorporate promising technologies to communicate freely available, high-priority, high-quality content, which accelerates scientific progress and advances heart and ...

Figure 1. The natural history of aortic stenosis, emphasizing a long presymptomatic period and the dismal outcome once symptoms begin. AV indicates average. Adapted from Ross and Braunwald. 11 In the ...

Although the role of longer-term BP control to improve outcomes in patients with stroke is undisputed, BP management immediately after a stroke remains controversial. In an effort to resolve this ...