Hi-C技术源于染色体构象捕获(Chromosome Conformation Capture—3C)技术,以整个细胞核为研究对象,利用高通量测序技术,结合生物信息学方法,研究全基因组范围内整个染色质DNA在空间位置上的关系,揭示染色体的三维结构。2015年,美国国立卫生研究院(NIH ...
近几年,染色体三维结构作为崭新的研究方向,在疾病研究中的地位越来越重要,高分文章层出不穷。本月18号,来自英国Babraham研究所的科学家利用捕获Hi-C技术,发现了成千上万与特定疾病相关的新基因,包括类风湿性关节炎、1型糖尿病和Crohn氏病。小编先带 ...
2009). Hi-C is a 3C derivative, based on proximity ligation of cross-linked DNA with a biotin linker, which is used to pull down the fragments, followed by high-throughput sequencing. From eight ...
Former President Donald Trump said that, if elected, he would fire the special counsel who brought criminal cases against him ...
This aspect of hi-fi ownership is usually overlooked simply because everything seems to work properly and still makes a sound ...
Vice President Harris will give an address at the Ellipse in Washington, D.C., on Tuesday, one week before Election Day.
Our expert in-house reviews team tests hi-fi systems throughout the year and across the market, with every one benchmarked against its closest competitors. Naturally, only those that come out of our ...
It’s not just for USB-C-equipped iPhones. Any Android phone that lacks one or more of these codecs can benefit, as can any laptop (a USB-A to USB-C adapter is included). It also works with ...
a standard VGP reference genome is assembled using a combination of long-read sequencing, linked-read sequencing, optical mapping and Hi-C data in an automated workflow, and includes a final ...
JB Hi-Fi Limited is a music and electronic goods retailer in Australia. The Company operates stores at sites located in most Australian States. Products include consumer electronics, car sound ...