Increased prothrombin times induced by combined vitamin E and warfarin therapy may be managed by discontinuing vitamin E, and, if necessary, by administering vitamin K.
In patients with protein C and protein S deficiency, when warfarin therapy is started there is a more rapid fall in concentration of protein C (antigen and activity) than the other vitamin K ...
Vitamin K antagonists, such as warfarin, have an unpredictable pharmacokinetic profile and numerous food and drug interactions, which need frequent monitoring, creating a burden for patients and ...
A phase IIa trial has demonstrated that a structural analogue of warfarin is safe, tolerable, and efficacious. Investigators believe that this new anticoagulant, named tecarfarin, will be ...
Warfarin works by blocking an enzyme that activates vitamin K. With less active vitamin K available, fewer clotting factors are released and blood clots form more slowly. When a person on warfarin ...
Under the care and guidance of a healthcare provider, vitamin K might also be used in the treatment of several bleeding-relating conditions, including excess bleeding from taking too much of the blood ...
with clopidogrel as for triple therapy with warfarin (the trend showed partly opposing signals). In our opinion, triple therapy using acetylsalicylic acid (ASS), clopidogrel, and vitamin-K ...
Severe hemorrhage associated with oral anticoagulants—a prospective observational study of the clinical course during treatment with vitamin K antagonists or direct oral anticoagulants.