Women taking other agents for hot flashes, hormonal therapy other than tamoxifen, or antidepressants were excluded. The primary endpoints, hot flash frequency and severity, were documented in ...

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serotonin and norepinephrine reuptake inhibitors and gabapentin to decrease menopausal hot flashes. Are these nonhormonal treatment options a viable alternative to hormone replacement therapy?

“As the definitive physiology of hot flashes is not known, I believe it cannot be assumed that the efficacy of the new antidepressants for hot flashes is a class effect,” says lead researcher ...