Hi-C技术源于染色体构象捕获（Chromosome Conformation Capture—3C）技术，以整个细胞核为研究对象，利用高通量测序技术，结合生物信息学方法，研究全基因组范围内整个染色质DNA在空间位置上的关系，揭示染色体的三维结构。2015年，美国国立卫生研究院（NIH ...

近几年，染色体三维结构作为崭新的研究方向，在疾病研究中的地位越来越重要，高分文章层出不穷。本月18号，来自英国Babraham研究所的科学家利用捕获Hi-C技术，发现了成千上万与特定疾病相关的新基因，包括类风湿性关节炎、1型糖尿病和Crohn氏病。小编先带 ...

It predicts CNV events from Hi-C data by linear model and graph neural network for modeling the complex interactions and ...

2009). Hi-C is a 3C derivative, based on proximity ligation of cross-linked DNA with a biotin linker, which is used to pull down the fragments, followed by high-throughput sequencing. From eight ...

基于不同类型的ADHD儿童，认知障碍影响不同，在治疗上也应采用差异化的治疗方式。以提升数学能力为例，ADHD儿童的数学计算能力相比于正常儿童更差，计算速度与大脑工作内存资源关系较为密切，其受到工作记忆功能的影响。脑工作内存资源关系较为密切，其受到工作 ...

WH editors talked to a gastroenterologist and registered dietitians to see if prebiotic sodas like Olipop and Poppi actually ...

As urban areas across the U.S. expand, many cities are trying to reduce their environmental impact while promoting ...

Georgian government officials raided the homes of local staff of an American think tank who work on tracking Russian ...

In this episode of our Health Innovators series, Paul Tunnah is joined by tech entrepreneur Fredrik Debong. Fredrik is the founder of Hi.Health app which enables customers of private health ...

BBC Sport Academy nutritionist Matt Lovell reveals why baked beans can help you live longer. Many people think it is a myth that baked beans are healthy but let me just confirm that the rumour is true ...

Are you an ambitious, dedicated student committed to meeting your academic and professional goals as quickly as possible? Michigan Tech students with a bachelor's degree can fast-track their career or ...