Hi-C技术源于染色体构象捕获(Chromosome Conformation Capture—3C)技术,以整个细胞核为研究对象,利用高通量测序技术,结合生物信息学方法,研究全基因组范围内整个染色质DNA在空间位置上的关系,揭示染色体的三维结构。2015年,美国国立卫生研究院(NIH ...
近几年,染色体三维结构作为崭新的研究方向,在疾病研究中的地位越来越重要,高分文章层出不穷。本月18号,来自英国Babraham研究所的科学家利用捕获Hi-C技术,发现了成千上万与特定疾病相关的新基因,包括类风湿性关节炎、1型糖尿病和Crohn氏病。小编先带 ...
2009). Hi-C is a 3C derivative, based on proximity ligation of cross-linked DNA with a biotin linker, which is used to pull down the fragments, followed by high-throughput sequencing. From eight ...
Those who frequent the Golden Arches are no stranger to a secret menu item. From the "Flying Dutchman" to the "McBrunch ...
The drinks sell in flavors including Hi-C Orange Lavaburst, Powerade Mountain Berry Blast, Hi-C Flashin’ Fruit Punch and Minute Maid Strawberry Lemonade. There’s also an option to order Creamy ...