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23 小时
CRM:乳酸终于出卖了肿瘤!科学家发明新型给药系统,专打产生乳酸 ...
*仅供医学专业人士阅读参考肿瘤通过有氧糖酵解(瓦博格效应)产生的乳酸,简直是恶贯满盈。我们曾经介绍过,乳酸可以将瘤内的巨噬细胞从抗癌型变成促癌型[1-3],可以增强调节性T细胞的免疫抑制功能[4],还能把PD-1抑制剂变成促进免疫抑制的“毒药”[5] ...
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