注射羊水干细胞可通过促进受损肾小管细胞增殖和减少细胞凋亡来改善动物急性肾小管坏死的急性期，但这些干细胞是否对 CKD 有益尚不清楚。 在这里，我们使用 Alport 综合征小鼠模型 Col4a5(-/-) 小鼠来确定羊水干细胞是否可以改变进行性肾纤维化的进程。

最佳的心脏功能取决于适当协调的心脏传导系统（CCS）。 CCS 是一组专门的细胞，负责产生心律并将这些信号有效地传导到 ...

尽管大多数人都知道骨质疏松症是由于雌激素缺乏和衰老导致的骨质脆性增加的疾病，但大多数人并没有意识到这种疾病的高风险和高成本。 据估计，美国每年发生的骨折中有近 30% 是由骨质疏松症引起的（Schwartz & Kagan (2002)）。加利福尼亚州是 65 岁以上人口 ...

Jonathan Thomas, PhD, JD, is President and CEO of the California Institute for Regenerative Medicine (CIRM). Thomas was previously the Chair of the CIRM governing Board from June 2011 to March 2023.

The last thing Maria Torres expected was to be diagnosed with type 2 diabetes. She exercised, ate well and kept her weight under control. There had to be some mistake. Maria asked her doctor to repeat ...

If you would like to contact CIRM regarding questions you may have about employment opportunities, please contact us at jobs@cirm.ca.gov. CIRM encourages job seekers to apply for specific job openings ...

San Francisco, CA – California’s stem cell agency, the California Institute for Regenerative Medicine (CIRM) today approved $150 million in new funding to help move promising stem cell-based therapies ...

CIRM has one singular mission: Accelerating world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse California and world. A dedication to ...

Researchers at the California Institute for Biomedical Research (CALIBR) have been awarded $8.447 million to test KA34, a drug that, in preclinical tests, recruits stem cells to create new cartilage ...

Our Agency funds clinical trials testing promising stem cell or gene therapies for currently incurable diseases or disorders to help patients with unmet medical needs. For basic information about stem ...

have the ability to divide and create an identical copy of themselves, a process called self-renewal; and can also divide to form cells that mature into cells that make up every type of tissue and ...

The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world-class science to deliver transformative regenerative medicine treatments in an equitable manner to a ...