Background The natural history and time course of the onset of exacerbation events of chronic obstructive pulmonary disease (COPD) is incompletely understood. Methods A prospective cohort of 212 ...

Superseded By 2013 Guideline: British Thoracic Society Guidelines on Diagnostic Flexible Bronchoscopy. Thorax 2001 Feb; 56(Suppl 1): 1–21.

Correspondence to British Thoracic Society, 17, Doughty Street, London WC1N 2PL, UK; bts{at}brit-thoracic.org.uk and Dr Charlotte E Bolton, Nottingham Respiratory Research Unit, University of ...

Background Despite biomarker-guided initiation, non- or loss of response to biologic therapy occurs in a minority of patients with severe asthma. In cases of treatment failure, it is important to ...

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Background Acute type 2 respiratory failure (AT2RF) is the failure of ventilatory mechanism which results in hypercapnia(>6kPa). Current treatment is non-invasive ventilation(NIV) which has a high ...

Background Development of emphysema and vascular stiffness in chronic obstructive pulmonary disease (COPD) may be due to a common mechanism of susceptibility to pulmonary and systemic elastin ...

Air Travel Working Party: Dr R K Coker (chair), Dr D A R Boldy, Dr R Buchdahl, Mr D Cramer, Professor D Denison, Wing Commander D P Gradwell, Professor J M B Hughes, Dr J A Innes, Dr A O C Johnson, Dr ...

2 Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands 3 Department of General Practice, University Medical Center Groningen, University of Groningen, ...

Department of Child Health, University of Leicester School of Medicine, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, P O Box 65, Leicester LE2 7LX, UK BACKGROUND The aim of ...

BACKGROUND Obstructive sleep apnoea (OSA) has been shown to be associated with an increased risk of road traffic accidents (RTAs). Predicting the driving ability and risk of RTAs in an individual with ...

1 Respiratory Muscle Laboratory, Guy’s, King’s and St Thomas’ School of Medicine, King’s College Hospital, London, UK Background: Although quadriceps weakness is well recognised in chronic obstructive ...