Way back in Week 4, 49ers rookie guard Dominick Puni had the wind knocked out of him and had to miss a snap. He hasn’t been ...

Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions ...

Nolan Bianchi, John Niyo, Richard Silva and Bob Wojnowski of The Detroit News offer predictions for Monday's Lions-49ers game ...

With nothing left to play for this season, the 49ers will have to hope that Brock Purdy grows from a challenging 2024 ...

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The NFL Week 17 schedule ends with a rematch of the 2023 NFC Championship game when the Detroit Lions travel to the West ...

The San Francisco 49ers are set to host the Detroit Lions at Levi's Stadium in Santa Clara, California, on Monday, December ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

To make matters worse, offensive lineman Spencer Burford, who was supposed to start at left tackle with Williams and his ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

The Lions will face a 49ers offensive line that could be starting two tackles signed off practice squads this week ...