The San Francisco 49ers will host the Detroit Lions on Monday Night Football. The schedule makers were probably envisioning a ...

Ahead of a massive showdown with the rival Minnesota Vikings to wrap up the regular season, the Detroit Lions flexed their NFC might on Monday night to take down the San Francisco 49ers.

NFL.com's Coral Smith breaks down four things to watch for when the San Francisco 49ers host the Detroit Lions on Monday night.

The Lions and 49ers kick off tonight at 5:15 p.m. PT (8:15 p.m. ET) on ABC, ESPN and ESPN Plus. Looking for the ManningCast?

The Detroit Lions play the San Francisco 49ers during this week's Monday Night Football game, here's how to watch.

Exclusive interview with New Orleans Saints interim head coach Darren Rizzi ahead of the Saints' game against the Las Vegas ...

New Orleans Saints defensive end Cameron Jordan's postgame interview after the Saints' loss vs. the Las Vegas Raiders in Week ...

San Francisco 49ers' George Kittle (Image credit: Thearon W. Henderson/Getty Images) The final regular season Monday Night Football game of the year (there will be a playoff game hosted by the MNF ...

What channel is Monday Night Football on? How to watch NFL Week 17 game between Detroit Lions, San Francisco 49ers on TV, ...

The streamer will offer a special presentation of a Wild Card playoff game on either Saturday, January 11 or Sunday, January ...

On the eve of facing the San Francisco 49ers on Monday Night Football, the Detroit Lions made a pair of roster moves to shore ...