San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers' season finale versus the Arizona ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

San Francisco 49ers running back Isaac Guerendo (knee, ankle) exited during the first quarter of Sunday's Week 18 game ...

Rookie running back Isaac Guerendo was carted off the field early in the 49ers’ season finale in Arizona against the ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started ...

Guerendo won't return to Sunday's game at Arizona due to knee and ankle injuries. Guerendo had his left leg twisted under him on his second carry of the game, and his teammates quickly motioned to the ...

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

The San Francisco 49ers entered Sunday's season finale against the Arizona Cardinals with a depleted roster. Quarterback Josh Dobbs took the reins in place ...

RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions ...

There are numerous player prop betting options on Isaac Guerendo for the 8:15 PM ET game Monday, which airs live on ABC/ESPN.

Should I start or sit Isaac Guerendo for fantasy football in Week 17? Read our fantasy football start 'em, sit 'em picks and ...