Direct Oral Anticoagulants (DOACs) have significantly improved anticoagulation therapy – due to their ease of use, predictable pharmacokinetics, and a reduced risk of certain adverse effects compared ...
Aging is associated with the progressive impairment of multi-organ function, which can impact the pharmacokinetics of antimicrobials, potentially leading to the failure of anti-infective therapy. With ...
A committee member pointed out that, although the design of the trial was appropriate when it was started, ximelagatran should be compared with warfarin in view of the current data on the efficacy ...