The tricyclic antidepressants have a higher rate of Q-T interval prolongation than do selective serotonin-reuptake inhibitors (SSRIs), particularly at higher concentrations and in cases of overdose.
The first antidepressants based upon reuptake inhibition, called tricyclic antidepressants (TCAs), were introduced in the mid-1950s (Pacher & Kecskemeti, 2004). Pharmacotherapy for the treatment ...
Results were similar for selective serotonin reuptake inhibitors and tricyclic antidepressants separately. Conclusion: Initiation of any antidepressant therapy was associated with a higher risk of PD ...
Tegretol and Lamictal are antiepileptic drugs that also treat other conditions. Learn more about the differences and similarities between the two drugs.