8 There is a consensus that csDMARDs are the mainstay of RA treatment, and the 2019 update of the EULAR recommendations supported the use of methotrexate as the first-line DMARD. 8 If there is ...
Leflunomide is the only nonbiologic DMARD developed specifically for the treatment of RA. It is an isoxazole derivative and its active metabolite, teriflunomide (formerly known as A77 1726), acts ...
RA treatment aims to decrease inflammation, which decreases symptoms (pain/discomfort and stiffness), and lessens the risk of joint damage. By limiting joint damage, disability is reduced. The primary ...