Hi-C技术源于染色体构象捕获（Chromosome Conformation Capture—3C）技术，以整个细胞核为研究对象，利用高通量测序技术，结合生物信息学方法，研究全基因组范围内整个染色质DNA在空间位置上的关系，揭示染色体的三维结构。2015年，美国国立卫生研究院（NIH ...

近几年，染色体三维结构作为崭新的研究方向，在疾病研究中的地位越来越重要，高分文章层出不穷。本月18号，来自英国Babraham研究所的科学家利用捕获Hi-C技术，发现了成千上万与特定疾病相关的新基因，包括类风湿性关节炎、1型糖尿病和Crohn氏病。小编先带 ...

2009). Hi-C is a 3C derivative, based on proximity ligation of cross-linked DNA with a biotin linker, which is used to pull down the fragments, followed by high-throughput sequencing. From eight ...

Emily Alberts/Daily. Buy this photo. It’s been 10 years since the last time the Michigan football team was forced to part with the Little Brown Jug. In 2014, Minnesota marched into Ann Arbor and ...

For the last 18 seasons, Mankato West has defeated Mankato East in the annual Jug football game. This time, however, will be ...

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A former associate editor with the Times of India, Jug Suraiya writes two regular columns for the print edition, Jugular Vein, which appears every Friday, and Second Opinion, which appears on ...