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Calcium and integrin-binding protein 2 (CIB2) and CIB3 bind to transmembrane channel-like 1 (TMC1) and TMC2, the pore-forming subunits of the inner-ear mechano-electrical transduction (MET) apparatus.
Cell debris was removed by centrifugation (12,000 rpm, 4 °C for 15 min) and the resulting supernatant was collected for further analysis. Prior to sample treatment for AA analysis, parts of the ...