In April 2024, the final report of the Cass Review, an independent review chaired by Dr Hilary Cass, was published, offering ...

Background Delayed recognition of clinical deterioration can result in harm to patients. Parents/carers can often recognise ...

Background Treatment to suppress or lessen effects of puberty are outlined in clinical guidelines for adolescents ...

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...

AIMS To evaluate the effects of discontinuing growth hormone (GH) treatment on energy expenditure and body composition, which might help predict those most likely to benefit from early reintroduction ...

Fibre is an essential nutrient in the human diet that is crucial for human health. It provides a range of functional benefits, including stool bulking, and physiological benefits through fermentation ...

Recently, two important papers on paediatric trauma were published by investigators from the Paediatric Emergency Care ...

2 Charles Salt Research Centre, Robert Jones and Agnes Hunt Orthopaedic & District Hospital NHS Trust, Oswestry, Shropshire SY10 7AG, UK 3 Department of Clinical Chemistry, University of Oulu, Oulu, ...

Objective To determine the safety of ciprofloxacin in paediatric patients in relation to arthropathy, any other adverse events (AEs) and drug interactions. Methods A systematic search of MEDLINE, ...

Aims Syringe drivers are the principle method of giving continuous infusions of important drugs to patients. Many of these drugs are critical for the maintenance of normal physiology. Anecdotal ...

Introduction An overview is given on the use of microdosing/microtracing studies for the safer and faster development of drugs in children. In a microdosing study a ...

Paediatric Microbiology, Great Ormond Street Hospital for Children and UCL Institute of Child Health, London, UK N J Sebire, Department of Paediatric Pathology, Great Ormond Street Hospital for ...