Primary and review articles published in English were identified by a MEDLINE (1966-June 2003) search using the MeSH terms "hot flashes," "hot flushes," "menopause," and "serotonin reuptake inhibitor.

Women taking other agents for hot flashes, hormonal therapy other than tamoxifen, or antidepressants were excluded. The primary endpoints, hot flash frequency and severity, were documented in ...

“As the definitive physiology of hot flashes is not known, I believe it cannot be assumed that the efficacy of the new antidepressants for hot flashes is a class effect,” says lead researcher ...