Journal of Clinical Oncology - ASCO Publications
网页2024年10月1日 · Founded in 1964, the American Society of Clinical Oncology, Inc. (ASCO®) is committed to making a world of difference in cancer care. Through research, education, and promotion of the highest-quality, equitable patient care, ASCO works to conquer cancer and create a world where cancer is prevented or cured, and every …
Management of Immune-Related Adverse Events in Patients …
网页Immunotherapy has revolutionized the treatment of many different types of cancers. Immune checkpoint inhibitors (ICPis) targeting cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4), programmed cell death-1 (PD-1), and PD ligand 1 (PD-L1) work by preventing the receptors and ligands from binding to each other, thereby disrupting signaling so that T …
Current and Future Management of HER2-Positive Metastatic …
网页2021年6月2日 · Advanced breast cancer with overexpression and/or amplification of human epidermal growth factor receptor 2 (HER2) is a clinically aggressive subtype with poor survival outcomes. 1,2 However, with the introduction of trastuzumab, the survival rates have greatly improved. 1 Trastuzumab binds to the extracellular domain IV of HER2 …
Management of Cancer Therapy–Associated Oral Mucositis
网页2020年2月3日 · Mucositis is a common and feared complication of anticancer therapy that can affect up to 90% of certain populations of patients with cancer. Even seemingly uncomplicated mucositis, which is often self-limited, can result in intense patient discomfort and decline in quality of life.
Treatment of Metastatic Colorectal Cancer: ASCO Guideline
网页2022年10月17日 · Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. 1 Almost 150,000 new cases and more than 50,000 deaths from CRC are reported each year in the United States. 2 In recent decades, the overall incidence of CRC has decreased among older adults because of screening and lifestyle factors; …
Nutrition in Cancer Care: A Brief, Practical Guide With a Focus on ...
网页2021年1月14日 · Although the diagnostic criteria of malnutrition may differ depending on the tool that is used, the prevalence of malnutrition was reported in several surveys as being up to 50% among hospitalized patients with cancer. 3,8-11 Furthermore, the severity of weight loss is an independent predictive factor for shorter overall survival 5; about 10%-20% of …
ASCO Publications
网页Founded in 1964, the American Society of Clinical Oncology, Inc. (ASCO®) is committed to making a world of difference in cancer care. Through research, education, and promotion of the highest-quality, equitable patient care, ASCO works to conquer cancer and create a world where cancer is prevented or cured, and every survivor is healthy.
Antiemetics: ASCO Guideline Update | Journal of Clinical Oncology
网页2020年7月13日 · The systematic reviews included 3 publications from the updated search and 10 publications on CPIs. Two phase III trials in adult patients with non–small-cell lung cancers evaluating a platinum-based doublet with or without the programmed death 1 (PD-1) inhibitor pembrolizumab recommended that all patients receive dexamethasone as a …
Evidence-Based Management of Oral Mucositis | JCO Oncology …
网页2020年2月3日 · As well described in the clinical review by Brown and Gupta 1 in this issue of JCO Oncology Practice, oral mucositis is a common toxicity of cancer therapy.The morbidity of oral mucositis includes pain, nutritional compromise, and infection risk, which potentially result in breaks or dose reductions in cancer therapy.
Updated Diagnostic Criteria and Staging System for Multiple …
网页2016年5月19日 · The diagnosis of MM requires 10% or more clonal plasma cells on bone marrow examination or a biopsy-proven plasmacytoma plus the presence of one or more myeloma-defining events. 10 Myeloma-defining events include the presence of one or more CRAB features, or one or more biomarkers of malignancy. The three biomarkers …